Engineered small extracellular vesicles displaying ACE2 variants on the surface protect against SARS-CoV-2 infection
Kim HK*, Cho J*, Kim E, Kim J, Yang JS, Kim KC, Lee JY, Shin Y, Palomera LF, Park J, Baek SH, Bae HG, Cho Y, Han J, Sul JH, Lee J, Park JH, Cho YW, Lee W†, and Jo DG†.
J Extracell Vesicles 2022
Extracellular vesicles from adipose tissue-derived stem cells alleviate osteoporosis through osteoprotegerin and miR-21-5p
Lee KS*, Lee J*, Kim HK, Yeom SH, Woo CH, Jung YJ, Yun YE, Park SY, Han J, Kim E, Sul JH, Jung JM, Park JH, Choi JS†, Cho YW†, and Jo DG†
J Extracell Vesicles 2021
Alzheimer's disease-causing presenilin-1 mutations have deleterious effects on mitochondrial function
Han J, Park H, Maharana C, Gwon AR, Park J, Baek SH, Bae HG, Cho Y, Kim HK, Sul JH, Lee J, Kim E, Kim J, Cho YE, Park SY, Palomera LF, Arumugam TV, Mattson MP†, Jo DG†
Theranostics 2021
Reactive oxygen species-responsive dendritic cell-derived exosomes for rheumatoid arthritis
Lee ES, Sul JH, Shin JM, Shin S, Lee JA, Kim HK, Cho Y, Ko H, Son S, Lee J, Park S, Jo DG†, Park JH†
Acta Biomater. 2021
O-GlcNAcylation ameliorates the pathological manifestations of Alzheimer's disease by inhibiting necroptosis
Park J, Ha HJ, Chung ES, Baek SH, Cho Y, Kim HK, Han J, Sul JH, Lee J, Kim E, Kim J, Yang YR, Park M, Kim SH, Arumugam TV, Jang H, Seo SW, Suh PG, Jo DG
Sci. Adv. 2021
Cell reprogramming using extracellular vesicles from differentiating stem cells into white/beige adipocytes
Jung YJ*, Kim HK*, Cho Y, Choi JS, Woo CH, Lee KS, Sul JH, Lee CM, Han J, Park JH, Jo DG†, Cho YW†
Sci. Adv. 2020
Small extracellular vesicles from human adipose-derived stem cells attenuate cartilage degeneration
Woo CH, Kim HK, Jung GY, Jung YJ, Lee KS, Yun YE, Han J, Lee J, Kim WS, Choi JS, Yang S, Park JH, Jo DG†, Cho YW†
J Extracell Vesicles 2020
Neuronal Aquaporin 1 inhibits amyloidogenesis by suppressing the interaction between beta-secretase and amyloid precursor protein
Park J, Madan M, Chigurupati S, Baek SH, Cho Y, Mughal MR, Yu A, Chan SL, Pattisapu JV, Mattson MP, Jo DG
J Gerontol A Biol Sci Med Sci 2020
O-GlcNAcylation as a therapeutic target for Alzheimer's disease
Park J, Lai MKP, Arumugam TV†, Jo DG†
Neuromolecular Med 2020
Intermittent fasting increases adult hippocampal neurogenesis
Park J, Lai MKP, Arumugam TV†, Jo DG†
Brain Behav 2020
NRF2/ARE pathway negatively regulates BACE1 expression and ameliorates cognitive deficits in mouse Alzheimer's models
Bahn G*, Park JS*, Yun UJ*, Lee YJ, Choi Y, Park JS, Baek SH, Choi BY, Cho YS, Kim HK, Han J, Sul JH, Baik SH, Lim J, Wakabayashi N, Bae SH, Han JW, Arumugam TV, Mattson MP†, Jo DG†
Proc Natl Acad Sci U S A 2019
Therapeutic approaches to Alzheimer's disease through modulation of NRF2
Bahn G, Jo DG
Neuromolecular Med 2019
Mulberry fruit extract ameliorates nonalcoholic fatty liver disease (NAFLD) through inhibition of mitochondrial oxidative stress in rats
Yang DK, Jo DG
Evid Based Complement Alternat Med 2018
Inhibition of Notch1 induces population and suppressive activity of regulatory T cell in inflammatory arthritis
Choi BY, Choi Y, Park JS, Kang LJ, Baek SH, Park JS, Bahn G, Cho Y, Kim HK, Han J, Sul JH, Baik SH, Hyun DH, Arumugam TV, Yang S, Han JW, Kang YM, Cho YW, Park JH, Jo DG
Theranostics 2018
Notch signaling and neuronal death in stroke
Arumugam TV†, Baik SH, Balaganapathy P, Sobey CG, Mattson MP, Jo DG†.
Prog Neurobiol 2018
Inhibition of Drp1 ameliorates synaptic depression, Aβ deposition, and cognitive impairment in an Alzheimer's disease model
Baek SH, Park SJ, Jeong JI, Kim SH, Han J, Kyung JW, Baik SH, Choi Y, Choi BY, Park JS, Bahn G, Shin JH, Jo DS, Lee JY, Jang CG, Arumugam TV, Kim J, Han JW, Koh JY, Cho DH, Jo DG
J Neurosci 2017
Interplay between Notch and p53 promotes neuronal cell death in ischemic stroke
Balaganapathy P, Baik SH, Mallilankaraman K, Sobey CG, Jo DG†, Arumugam TV†
J Cereb Blood Flow Metab 2017
Notch1 deficiency decreases hepatic lipid accumulation by induction of fatty acid oxidation.
Song NJ, Yun UJ, Yang S, Wu C, Seo CR, Gwon AR, Baik SH, Choi Y, Choi BY, Bahn G, Kim S, Kwon SM, Park JS, Baek SH, Park TJ, Yoon K, Kim BJ, Mattson MP, Lee SJ, Jo DG†, Park KW†
Sci Rep 2016
Emerging roles of the γ-secretase-notch axis in inflammation
Cheng YL, Choi Y, Sobey CG, Arumugam TV, Jo DG†
Pharmacol Ther 2015
Pin1 promotes neuronal death in stroke by stabilizing Notch intracellular domain
Baik SH, Fane M, Park JH, Cheng YL, Yang-Wei Fann D, Yun UJ, Choi Y, Park JS, Chai BH, Park JS, Back SH, Jeong JI, Jang YJ, Bahn G, Lee JY, Li YI, Sobey CG, Uchida T, Park JH, Kim HT, Tang SC, Arumugam TV†, Jo DG†
Ann Neuro 2015
Notch1 targeting siRNA delivery nanoparticles for rheumatoid arthritis therapy
Kim MJ, Park JS, Lee SJ, Jang J, Park JS, Back SH, Bahn G, Park JH, Kang YM, Kim SH, Kwon IC, Jo DG†, Kim K†
J Control Release 2015
Evidence that neuronal Notch-1 promotes JNK/c-Jun activation and cell death following ischemic stress
Cheng YL, Choi Y, Seow WL, Manzanero S, Sobey CG, Jo DG†, Arumugam TV†
Brain Res 2014
Hyaluronan nanoparticles bearing γ-secretase inhibitor: in vivo therapeutic effects on rheumatoid arthritis
Heo R, Park JS, Jang HJ, Kim SH, Shin JM, Suh YD, Jeong JH, Jo DG† Park JH†
J Control Release 2014
A hyaluronic acid-methotrexate conjugate for targeted therapy of rheumatoid arthritis
Shin JM, Kim SH, Thambi T, You DG, Jeon J, Lee JO, Chung BY, Jo DG†, Park JH†
Chem Commun (Camb) 2014
Evidence that Collaboration between HIF-1α and Notch-1 Promotes Neuronal Cell Death in Ischemic Stroke
Cheng YL, Park JS, Manzanero S, Choi Y, Baik SH, Okun E, Gelderblom M, Fann DY, Magnus T, Launikonis BS, Mattson MP, Sobey CG, Jo DG†, Arumugam TV†
Neurobiol Dis 2014
Inhibition of Notch signalling ameliorates experimental inflammatory arthritis
Park JS, Kim SH, Kim K, Jin CH, Choi KY, Jang J, Choi Y, Gwon AR, Baik SH, Yun UJ, Chae SY, Lee S, Kang YM, Lee KC, Arumugam TV, Mattson MP, Park JH, Jo DG
Ann Rheum Dis 2013